GOAT ANTI HUMAN NOXA MBS224213 from MyBioSource.com

Description

MBS224213 specifically recognises human Noxa, a mitochondrial localised protein and member of the BH3-only proapoptotic protein family, which is up-regulated by p53, IFNbeta, phorbol esters, dsRNA and viruses, and acts as promoter of caspase and apoptosis activation. Noxa is a transcriptional target of p53, p73 and BH3-only proteins, and competes with, and displaces, the proapoptotic proteins BAK1, and BIM, from the antiapoptotioc protein MCL1 (Bcl-2-related protein EAT/mcl1), thereby influencing apoptosis versus cell survival

Product Specs
ItemGOAT ANTI HUMAN NOXA
CompanyMyBioSource.com
Price Pricing Info Supplier Page View Company Product Page
Catalog NumberMBS224213
Quantity0.1 mg
ApplicationsELISA (EIA), Western Blot (WB)
ConcentrationIgG concentration 0.5mg/ml
Conjugate/TagUnconjugated
FormatPurified
Purified IgG - liquid
TargetNOXA
IsotypeIgG
Molecular Weight14,955 Da
HostGoat
ImmunogenThis item specifically recognises human Noxa, a mitochondrial localised protein and member of the BH3-only proapoptotic protein family, which is up-regulated by p53, IFNbeta, phorbol esters, dsRNA and viruses, and acts as promoter of caspase and apoptosis activation.

Noxa is a transcriptional target of p53, p73 and BH3-only proteins, and competes with, and displaces, the proapoptotic proteins BAK1, and BIM, from the antiapoptotioc protein MCL1 (Bcl-2-related protein EAT/mcl1), thereby influencing apoptosis versus cell survival
NCBI Full Gene Namephorbol-12-myristate-13-acetate-induced protein 1
NCBI Gene AliasesAPR, NOXA
ClonalityPolyclonal